NCATS | National Center for Advancing Translational Sciences
Warren CaseyPh.D.
NIH | National Institute of Health
Russell ThomasPh.D.
EPA | U.S. Environment Protection Agency
Suzanne FitzpatrickPh.D.
FDA | U.S. Food and Drug Administration
Assay Evaluation and Screening
Identify toxicity pathways & corresponding assays
Review nominated assays
Prioritize assays for qHTS
Co-Chairs
Menghang XiaPh.D.
NCATS | National Center for Advancing Translational Sciences
Kristine WittM.S.
NTP | National Toxicology Program
Michael SantilloPh.D.
FDA | U.S. Food and Drug Administration
Chemical Selection
Establish compound libraries for qHTS (10K, mixtures, water-soluble)
Establish library QC procedures for identity, purity, concentration, and stability
Co-Chairs
Katherine CoutrosPh.D.
EPA | U.S. Environmental Protection Agency
Ruili HuangPh.D.
NCATS | National Center for Advancing Translational Sciences
Suramya WaidyanathaPh.D.
NTP | National Toxicology Program
Donna MendrickPh.D.
FDA | U.S. Food and Drug Administration
Communications Team
Provide both external and internal communications support for the Tox21 program
Co-Chairs
Monica LinnenbrinkM.P.A.
EPA | U.S. Environment Protection Agency
Anna RossoshekM.S., M.B.A.
NCATS | National Center for Advancing Translational Sciences
Sebastian Cianci
FDA | U.S. Food and Drug Administration
Program Highlights
Tox21 Assay Recognized in Society for Laboratory Automation and Screening (SLAS) Top Ten List
For their work developing a new assay to identify molecules that block angiogenesis in special screening plates Tox 21 collaborators were awarded with a spot on the 2018…
Tox21 Scientists Teach Continuing Education Courses at the Society of Toxicology’s Annual Conference
As part of their participation in the Annual Society of Toxicology (SOT) conference, Tox21 collaborators participated in SOT’s Continuing Education program. SOT offers a wide range of courses…
Tox21 Scientists Prioritize Compounds to Advance Research on Mitochondrial Damage
As part of the Tox21 collaboration, scientists developed of an analytical approach to enable researchers to prioritize environmental chemicals for their ability to disrupt mitochondria, the power generators of…
Federal partners gathered at NIEHS in May 2018 to discuss the implementation of the new Tox21 strategic plan. https://factor.niehs.nih.gov/2018/6/science-highlights/tox21/index.htm
Tox21 collaborators have published a new strategic plan in the journal ALTEX to expand the scope of our research. Tox21 will be focusing research on five focus areas. Tox21…